The effects of actinomycin D and chloramphenicol on the rat preimplantation embryos |
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| Authors: | E Giavini M Prati C Vismara |
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| Institution: | (1) Institute of Zoology, Laboratory of Embryology and Experimental Morphology, University of Milano, Via Celoria 10, I-20133 Milano, (Italy) |
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| Abstract: | Summary Actinomycin D and chloramphenicol, injected in the rat on day 3 or 4 of gestation, induce embryolethality and embryotoxicity. These effects are revealed on day 5 of pregnancy by reduced number of blastocysts and by decrease of mean blastomeres number. |
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