Voltammetric determination of estrogens based on the enhancement effect of surfactant at carbon paste electrode |
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Authors: | Wu Kang-bing He Qiong Hu Sheng-shui |
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Institution: | (1) College of Chemistry and Molecular Sciences, Wuhan University, 430072 Wuhan, Hubei, China;(2) Department of Chemistry, Qujing Normal College, 655000 Qujing, Yunnan, China |
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Abstract: | Highly sensitive voltammetric method for the determination of estrogens, based on the enhancement effect of cetyltrimethylammonium
bromide (CTAB) has been described. In the presence of CTAB, the oxidation peak currents of estrogens (estradiol, estrone,
estriol, estradiol valerate and diethylstilbestrol) as the carbon paste electrode (CPE) increased significantly after open-circuit
accumulation. The peak current was proportional to the concentration of estradiol over the range from 5×10−9 to 2.5×10−6 mol·L−1. The detection limit was 8×10−10 mol·L−1 at 6 min of accumulation. The total amounts of estrogens in the blood serums were determined and the average recovery was
104.92%. Under the conditions used, the electrode process of estradiol was examined the mechanism for peak current enhancement
was also discussed.
Foundation item: Supported by the National Natural Science Foundation of China (60171023) and the Natural Science Foundation
of Hubei Province (99J060)
Biography: Wu Kang-bing(1977-), male, Ph.D. candidate. research direction: bioelectrochemistry. |
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Keywords: | estrogen determination surfactant carbon paste electrode |
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