Distinct t(7;9)(q34;q32) breakpoints in healthy individuals and individuals with T-ALL |
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| Authors: | Marculescu Rodrig Vanura Katrina Le Trang Simon Paul Jäger Ulrich Nadel Bertrand |
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| Institution: | Department of Internal Medicine I, Division of Hematology, University of Vienna, W?hringer Gürtel 18-20, A-1090 Vienna, Austria. |
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| Abstract: | After V(D)J-mediated translocations, signal joints are retained on one of the derivative chromosomes. We report here that such signal joints are highly reactive and constitute unstable genomic elements with potential oncogenic properties. |
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