Synthesis and properties of benzo [d,e]estra-1,3,5(10)-triene-3,17β-diol 17-acetate |
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Authors: | P. P. Castelli R. Vitali G. Briziarelli R. Gardi |
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Affiliation: | (1) Vister Research Laboratories, I-22064 Casatenovo Como, Italy;(2) Blasinachim S.p.A., Milano, Italy;(3) Present address: Farnex Laboratori S.p.A., Codogno, Italy;(4) Present address: Schering Corporation, Lafayette, New Jersey, USA |
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Abstract: | Summary A new pentacyclic analogue of estradiol, benzo[d, e]estradiol 17-acetate, has been prepared and investigated for its hormonal and antitumor activity. Unlike related testosterone derivatives, the new compound did not display any interesting property. |
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