人体肺动脉狭窄血流动力学数值分析

采用计算流体动力学方法,探讨针对同一模型不同主肺动脉狭窄率(0,25%和50%)的血流动力学变化情况.通过对患者CT数据处理,完成了三组肺动脉狭窄几何的全三维数字化重构,结合主肺动脉血流量等临床数据,模拟了伴有不同狭窄程度的肺动脉模型内血流细节.仿真结果得到了连接段内血液流动速度场、压力、壁面剪切应力等分布特性,这对于评判不同肺动脉狭窄程度的影响和相关手术治疗方案的选择有着参考作用.

Effects of Stenosis on Hemodynamics within Pulmonary Artery Models: Numerical Simulation Studies

The purpose of the study is to investigate the influence of different main pulmonary artery (MPA) stenosis rate (0, 25%, and 50%) on the hemodynamic features within three pulmonary artery (PA) models using computational fluid dynamics (CFD). In these simulations, one three-dimensional stenosed model was reconstructed from the computer tomography (CT) images, and the other two were acquired by changing the degree of stenosis based on the geometry reconstructed. A velocity profile was used together with a pulsatile waveform according to recorded clinical data as the inflow condition, and transient CFD simulations were performed on these three PA models. The results are presented for a better understanding of the flow characteristics such as distributions of the flow pattern, pressure drop and wall shear stress in the stenosed PA models, which may be the primary variable for evaluating the effect of different levels of MPA stenosis rate and consequently optimizing the surgical deign.