Inhibition of DNA synthesis in concanavalin A stimulated rat lymph node cells by serum from arthritic rats |
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| Authors: | L. Binderup E. Bramm E. Arrigoni-Martelli |
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| Affiliation: | (1) Dept. of Pharmacology, Leo Pharmaceutical Products, 2750 Ballerup, (Denmark) |
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| Abstract: | Summary Serum from adjuvant arthritic rats inhibits the mitogenic response of rat lymph node cells to concanavalin A, leaving unaffected the response to phytohemagglutinin. This activity is already evident 4 days after adjuvant administration and persists for at least 28 days. |
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