Regulation of mouse trophoblast giant cell nucleus development in hatched mouse blastocysts by cyclic cytidine 3',5'-monophosphate (cCMP) |
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| Authors: | P J Chan I Henig D R Tredway |
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| Institution: | Department of Obstetrics and Gynecology, Oral Roberts University School of Medicine, Tulsa, Oklahoma 74104. |
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| Abstract: | The dibutyryl analog of cCMP enlarged the nuclei of trophoblast giant cells and promoted blastocyst development. The result suggests that cCMP has a trophic effect on embryonic development, specifically by altering the size of the trophoblast cell nucleus but does not enhance trophoblast cell proliferation processes. |
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