超声辅助丙酮缩氨基脲的合成

目的研究一种方便、快速合成丙酮缩氨基脲（AS）的方法。方法以盐酸氨基脲和丙酮为原料，室温下超声辐射协助合成丙酮缩氨基脲。考察原料配比、超声辐射频率和反应时间对反应产率的影响。结果在最佳反应条件下（以swc：nacetooe=1：10，超声频率59kHz，反应时间40min）合成了丙酮缩氨基脲，收率可达85％。结论此法与常规的加热反应法相比，反应时间短，产物收率高，操作简单。

Synthesis of acetone semicarbazone under ultrasonic irradiation

Aim To seek a convenient, rapid synthetic method of acetone semicarbazone（AS）. Methods Acetone semicarbazone is synthesized under ultrasonic irradiation at room condition by u- sing semicarbazide hydrochloride （SHC） and acetone as raw materials. The effect of reactants molar ratio, ultrasound irradiation frequency and reaction time on the yields of acetone semicarhazone syn- thesis is studied. Results Acetone semicarbazone is synthesized under the optimum synthetic condi- tions （molar ratio of semicarbazide hydrochloride to acetone is 1 ： 10 （nsnc ： n = 1 ： 10）, and the ultrasonic radiation frequency is 59 kHz, the irradiation time is 40 min）. The yield is over 85%. Con- clusion Compared with the conventional heating reactions, this method features shorter reaction time, higher product yields and easier operation.