Similarities between metallothionein and low molecular weight testicular cadmium-binding protein |
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Authors: | Z A Shaikh P C Tewari |
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Institution: | (1) Department of Pharmacology and Toxicology, University of Rhode Island, 02881 Kingston, Rhode Island, USA |
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Abstract: | Summary The incorporation of35S-cysteine and3H-glutamic acid was studied in mouse hepatic and renal metallothionein and in testicular cadmium-binding protein of similar molecular weight. Preferential incorporation of35S-cysteine over3H-glutamic acid was observed not only in hepatic and renal metallothionein, but also in testicular cadmium-binding protein. When the antigenic reactivity of these proteins was compared, all three proteins reacted with the metallothionein antibody. These similarities suggest that the low molecular weight testicular cadmium-binding protein is apparently metallothionein. |
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Keywords: | Metallothionein cadmium cadmium-binding protein testis liver kidney |
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