Prostaglandin-like substances inPropionibacterium acnes. VI. Characterization of the lipid fraction by gas chromatography in conjunction with mass spectrometry |
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Authors: | S Abrahamsson L Hellgren J G A M Raaijmakers J Vincent |
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Institution: | (1) Department of Structural Chemistry, Faculty of Medicine, University of Göteborg, Göteborg, Sweden;(2) Department of Dermatology, Faculty of Medicine, University of Trondheim, Trondheim, Norway;(3) Research Laboratories, Gist-Brocades, Haarlem, The Netherlands |
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Abstract: | Summary The lipid fraction ofP. acnes was submitted to stepwise purification followed by bioassay in order to localize the prostaglandin-like material. GC-MS analysis revealed the occurrence of substances having a part but not a total molecule in common with the prostaglandin family, suggesting that prostaglandin-like substances represent a new group of prostaglandin compounds.The competent technical assistance of Mr N. Engström and Mr G.A. de Vogel is gratefully acknowledged. |
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