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Prostaglandin-like substances inPropionibacterium acnes. VI. Characterization of the lipid fraction by gas chromatography in conjunction with mass spectrometry
Authors:S Abrahamsson  L Hellgren  J G A M Raaijmakers  J Vincent
Institution:(1) Department of Structural Chemistry, Faculty of Medicine, University of Göteborg, Göteborg, Sweden;(2) Department of Dermatology, Faculty of Medicine, University of Trondheim, Trondheim, Norway;(3) Research Laboratories, Gist-Brocades, Haarlem, The Netherlands
Abstract:Summary The lipid fraction ofP. acnes was submitted to stepwise purification followed by bioassay in order to localize the prostaglandin-like material. GC-MS analysis revealed the occurrence of substances having a part but not a total molecule in common with the prostaglandin family, suggesting that prostaglandin-like substances represent a new group of prostaglandin compounds.The competent technical assistance of Mr N. Engström and Mr G.A. de Vogel is gratefully acknowledged.
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