| ~(125)I(~(131)I)标记血卟啉的研制 |
| |
| 引用本文： | 陆丽仪,兰庆平.~(125)I(~(131)I)标记血卟啉的研制[J].北京师范大学学报(自然科学版),1988(3). |
| |
| 作者姓名： | 陆丽仪 兰庆平 |
| |
| 作者单位： | 北京师范大学化学系，北京师范大学化学系 |
| |
| 摘 要： | 为了研究光敏剂血卟啉在组织内的分布状况及运动变化规律等,以提高疗效,按文献制备了放射性标记的血卟啉作为“示踪剂”。1 碘化标记1)氯胺T法:反应所用的氯胺T(ChT),Na_2S_2O_5,KI等均用0.2mol/L pH7.5PB溶解,临用前配制.小试管中放入血卟啉0.5mL(5mg/mL,针剂,中国医学科学院肿瘤研究所提供)、Na~(125)I(Na~(131)I)25μL(约2mCi)和ChT0.5mL(5mg/mL),搅拌下室温反
|
RADIOIODINATION OF HEMATOPORPHYRIN WITH ~(125)I(~(131)I) |
| |
| Lu Liyi Lan Qingping.RADIOIODINATION OF HEMATOPORPHYRIN WITH ~(125)I(~(131)I)[J].Journal of Beijing Normal University(Natural Science),1988(3). |
| |
| Authors: | Lu Liyi Lan Qingping |
| |
| Institution: | Department of Chemistry |
| |
| Abstract: | The preparation of ~(125)I(~(131)I) hematoporphyrin with the aid ChT and NBS radioiodination methods is described. Iodination efficciency is over 90%. Purification of the product is carried out by ether extraction, its radioche- mical purity is over 90% when it is examined using the silica gel thin plate assay. Title preparation is used in the tracer studies. |
| |
| Keywords: | hematopolphyrin radioiodination iodine 125 iodine 131 |
| 本文献已被 CNKI 等数据库收录！ |
|
