A modified non-homogeneous model for codon preference and primary sequence structure in protein-coding regions |
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Authors: | Han Le Mo Zhong-xi |
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Institution: | (1) School of Mathematics and Statistics, Wuhan University, 430072 Wuhan, Hubei, China |
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Abstract: | Based on non-homogeneous model, a modified model is proposed. The new model deals with codon preference in protein-coding
regions, reflects more accurately the key biological features of the regions. In addition, it is demonstrated, via an example,
the modified model offers better solutions than previous model does.
Foundation item: Supported by the Zi-qiang Science Foundation of Wuhan University
Biography: Han Le (1977-), female, Master candidate, research direction: optimization and bioinformatics |
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Keywords: | Markov chain transition matrix base sequence codon |
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