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两种抗应激剂对恒河猴抗热应激作用的试验研究
引用本文:赵远,和占龙,吴海兴,李云龙,王俊斌,陈丽雄,鲁帅尧. 两种抗应激剂对恒河猴抗热应激作用的试验研究[J]. 实验动物科学, 2008, 25(3): 30-33
作者姓名:赵远  和占龙  吴海兴  李云龙  王俊斌  陈丽雄  鲁帅尧
作者单位:1. 中国医学科学院,北京协和医学院医学生物学研究所,昆明,650118
2. 昆明市动物疾病预防控制中心,昆明,650118
摘    要:目的研究两种抗应激剂对恒河猴热应激的影响。方法将6只恒河猴随机分为A,B两组采血做9项血液学及9项血液生化指标测定,A组日粮中每只添加VC300 mg/d和VE50 mg/d;B组日粮中添加0.2%苜草素,饲喂两个月后分别将A、B两组恒河猴放入(32±1)℃,湿度70%猴房内,1 h后采血,测定相应血液学及血液生化指标。结果两组动物血液学各项指标试验前后差异不显著(P>0.05);而血液生化值呈现:A组试验后AST、ALP、LDH分别为(101±23.64)U/L,(623.67±233.12)U/L,(1384.33±807.66)U/L,试验前后差异不显著(P>0.05);B组试验后TP、ALB分别为(83.83±16.32)g/L,(38.53±0.57)g/L;试验前后差异不显著。结论VC和VE在恒河猴抗热应激过程中主要作用于维持血液中AST、ALP、LDH的活性稳定,而苜草素主要作用于维持血液中TP、ALB的稳定,两种添加剂能有效提高恒河猴抗热应激的能力。

关 键 词:恒河猴  热应激  抗应激剂  血液学  血液生化  
收稿时间:2008-06-28

Study of The Effects of Two Anti-stressors on Rhesus Monkeys in Heat-stressed
ZHAO Yuan,HE Zhan-long,WU Hai-xing,LI Yun-long,WANG Jun-bin,CHEN Li-xiong,LU Shuai-yao. Study of The Effects of Two Anti-stressors on Rhesus Monkeys in Heat-stressed[J]. Laboratory Animal Science, 2008, 25(3): 30-33
Authors:ZHAO Yuan  HE Zhan-long  WU Hai-xing  LI Yun-long  WANG Jun-bin  CHEN Li-xiong  LU Shuai-yao
Affiliation:ZHAO Yuan~1,HE Zhan-long~1,WU Hai-xing~2,LI Yun-long~2 WANG Jun-bin~1,CHEN Li-xiong~1,LU Shuai-yao~1(1.Institute of Medical Biology,Chinese Academy of Medical Sciences , Peking Union Medical College,Kunming 650118,China)(2.Kunming Centres of Animal for Diseases Control , Prevention,China)
Abstract:Objective Study of the effects of Two Anti-stressors on Rhesus Monkeys in heat-stressed . Methods Selected six health laboratory rhesus monkeys, and divided into group A, B, Nine hematological and nine blood biochemical were measured,A was added Vitamin C 300 mg/d and Vitamin E 50mg/d each in diets, B group was added mucaosu 0.2%, Two months later, Croup A and B was bred under the condition of (32 ± 1)℃,70% humidity for one hour, After that measured hematological and biochemical. Results Test cross-reference hematological was not significantly ( P 〉 0.05), After test, AST. ALP, LDH of group A were ( 101 ± 23.64) U/L, (623.67 ±233.12 ) U/L, (1384.33 ± 807.66)U/L and was not significant than before test (P 〉 0.05);After test, TP、 ALB of group B were (83.83 ± 16.32)g/L,(38.53 ±0.57)g/L and was not significant than before test (P 〉0.05). Conclusion Effects of Vitamin C and Vitamin E were stood balance of AST,ALP、LDH in blood on Rhesus Monkeys in heat-stressed,Mucaosu were stood balance of TP、ALB in blood, finding two anti-stressors had effects on development anti-hotstress on rhesus monkeys.
Keywords:Rhesus monkeys(Macaca mulatta)  Hotstress  Anti-stressor hematological  Serum biochemical  Mucaosu  
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