The influence of GABA on discharges of cortical epileptogenic focus |
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| Authors: | P Mare? J Mare? P Reme? M Hessler J Fischer |
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| Institution: | (1) Institute of Physiology, Czechoslovak Academy of Sciences, Bud jovická 1083, CS-142 20 Prague 4;(2) Institute of Physiology, Faculty of General Medicine, Charles University, Prague, (Czechoslovakia) |
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| Abstract: | Summary GABA, when applied locally, acted similarly on both primary and mirror cortical focus: the negative component of the spike discharge was suppressed or inverted in polarity, whereas the late slow negative wave was strongly potentiated. Recordings from deep cortical layers suggested a different origin of these 2 surface-negative components of focal discharges. |
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