N-Nitrosospermidine: the principal nitrosation product of spermidine |
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Authors: | Y Takeda H Kanaya |
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Institution: | (1) Food and Drug Safety Center, Hatano Research Institute, 257 Hadano, Kanagawa, Japan |
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Abstract: | Summary N-(4-Aminobutyl)-N-(3-aminopropyl)nitrosamine (N-nitrosospermidine) was identified as a major product in the reaction between spermidine and nitrous acid. N-Nitrosospermidine was not significantly mutagenic in the Ames assay.Acknowledgment. This work was supported in part by a Grant-in-Aid for Cancer Research (50-2) from the Ministry of Health and Welfare of Japan. |
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