| Protein adsorption on materials surfaces with nano-topography |
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| 作者姓名： | SONG Wei CHEN Hong |
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| 作者单位： | [1]School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China [2]State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China |
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| 基金项目： | Supported by the National Natural Science Foundation of China (Grant Nos. 90606013 and 20634030)，the Ministry of Science and Technology (Grant No. 107080) |
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| 摘 要： | Protein adsorption behavior on the surfaces of biomedical materials is highly related to the biocom- patibility of the materials. In the past, numerous research reports were mainly focused on the effect of chemical components of a material’s surface on protein adsorption. The effect of surface topography on protein adsorption, the topic of this review, has recently received keen interest. The influence of surface nano-topographic factors, including roughness, curvature and geometry, on protein adsorption as well as the protein adsorption behavior, such as the amount of protein adsorbed, the activity and morphology of adsorbed protein, is introduced.
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| 关 键 词： | 蛋白质 吸附 材料表面 地形图 生物适应性 |
| 收稿时间： | 2007-06-19 |
| 修稿时间： | 2007-10-08 |
Protein adsorption on materials surfaces with nano-topography |
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| SONG Wei CHEN Hong.Protein adsorption on materials surfaces with nano-topography[J].Chinese Science Bulletin,2007,52(23):3169-3173. |
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| Authors: | Wei Song Hong Chen |
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| Institution: | (1) School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, China;(2) State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, China |
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| Abstract: | Protein adsorption behavior on the surfaces of biomedical materials is highly related to the biocompatibility of the materials.
In the past, numerous research reports were mainly focused on the effect of chemical components of a material’s surface on
protein adsorption. The effect of surface topography on protein adsorption, the topic of this review, has recently received
keen interest. The influence of surface nano-topographic factors, including roughness, curvature and geometry, on protein
adsorption as well as the protein adsorption behavior, such as the amount of protein adsorbed, the activity and morphology
of adsorbed protein, is introduced.
Supported by the National Natural Science Foundation of China (Grant Nos. 90606013 and 20634030) and the Ministry of Science
and Technology (Grant No. 107080) |
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| Keywords: | nano-topography protein adsorption biocompatibility materials surfaces |
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