Uptake of noradrenaline in high altitude native's heart |
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Authors: | J R Rapin J Coudert L Drouet J Durand Y Cohen |
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Institution: | (1) Department of Pharmacology and Physiology, University Paris XI, Rue J. B. Clément, F-92290 Chatenay Malabry, (France) |
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Abstract: | Summary Uptake of3H-noradrenaline by the heart was studied with sections of isolated atria obtained from high or lowlanders. In native highlanders, affinity for3H-noradrenaline by human atria is more significant than in lowlanders. Furthermore, the Michaelis Menten constant is lower in high altitude native's heart. |
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