Monolayer cultures of normal adult rat adrenocortical cells: Steroidogenic responses to nucleotides,bacterial toxins and antimicrotubular agents

Summary Monolayer cultures of normal rat adrenocortical cells were treated with agents which stimulate steroidogenesis by Y-1 adrenal tumour cells. Choleragen was active, whereas cyclic nucleotides other than cyclic AMP, bacterial endotoxins and antimicrotubular agents were inactive.This work was supported by the Medical Research Council of Great Britain (grant No. 970/656/B). I am grateful to MissR. Magee for technical assistance and Prof.A. M. Neville for continued support.