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Two novel prolactin release-inhibiting 8α-amino-ergolines
Authors:E. Flückiger  U. Briner  H. R. Bürki  P. Marbach  H. R. Wagner  W. Doepfner
Affiliation:(1) Preclinical Research, Pharmaceutical Division, Sandoz Ltd, CH-4002, Basel, (Switzerland)
Abstract:Summary Prolactin secretion inhibition and changes in striatal dopamine metabolism in rats were compared after the administration of 8a-amino-ergoline CH 29-717 and 2 derivates. CQ 32-084 was similar to but less potent than CH 29-717. while 32-085, the 1-methyl derivative, showed delayed dopaminomimetic effects.
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