Two novel prolactin release-inhibiting 8α-amino-ergolines |
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Authors: | E. Flückiger U. Briner H. R. Bürki P. Marbach H. R. Wagner W. Doepfner |
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Affiliation: | (1) Preclinical Research, Pharmaceutical Division, Sandoz Ltd, CH-4002, Basel, (Switzerland) |
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Abstract: | Summary Prolactin secretion inhibition and changes in striatal dopamine metabolism in rats were compared after the administration of 8a-amino-ergoline CH 29-717 and 2 derivates. CQ 32-084 was similar to but less potent than CH 29-717. while 32-085, the 1-methyl derivative, showed delayed dopaminomimetic effects. |
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