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A new model of glucocorticoid-induced metanephric maldevelopment |
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| Authors: | E D Avner W E Sweeney N P Piesco D Ellis |
| Abstract: | A new experimental model of glucocorticoid-induced tubular cyst formation has been developed in metanephric organ culture. The addition of cortisol (1.4 X 10(-5) M) to chemically defined serum-free culture medium produces cystic changes during in vitro nephrogenesis . The model isolates the role of glucocorticoids in experimental cyst formation. |
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