Inability of dithiols to cause activation ofLimulus endotoxin sensitive procoagulase |
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Authors: | M. F. Scully Y. M. Newman V. V. Kakkar |
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Affiliation: | (1) Thrombosis Research Unit, King's College Hospital Medical School, Denmark Hill, SE5 8RX London, (England) |
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Abstract: | Summary Using a chromogenic substrate it has been shown that the endotoxin sensitive procoagulase ofLimulus lysate is not activated by dithiols. Increased turbidimetric readings in the presence of dithiols would therefore appear to be nonspecific. |
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