Responses of monkey,rabbit and dog internal carotid arteries to atrial natriuretic factor |
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Authors: | Y Kawai T Ohhashi |
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Institution: | (1) Department of Physiology, Shinshu University School of Medicine, 3-1-1 Asahi, 390 Matsumoto, Japan |
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Abstract: | Summary Effects of atrial natriuretic factor (ANF) on monkey, rabbit and dog internal carotid arteries were investigated. ANF caused a concentration-dependent relaxation in arterial strips submaximally precontracted with noradrenaline, 5-hydroxytryptamine, or high-potassium solution (10–30 mM). The response was greatest in the monkey arteries and least in the dog arteries. These results suggest that there is a marked species difference in the ANF-induced relaxation of the internal carotid arteries. |
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Keywords: | Atrial natriuretic factor (ANF) internal carotid artery vasodilation |
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