Tissue- and stage-specific RNA patterns inDrosophila as revealed by gradient formamide gel electrophoresis

Summary The in vitro labeled RNAs in the accessory glands from male adults, and in the salivary glands and fat body from developing larvae ofDrosophila melanogaster were separated on linear gradient acrylamide gels in formamide. The patterns appear to be tissue- and stage-specific, and several lines of evidence indicate that the visualized radioactive bands include both hnRNA and messages.Acknowledgments. The financial support by the Swiss National Science Foundation and the George and Antoine Claraz-Schenkung is gratefully acknowledged. I thank Prof. Max Birnstiel for providing me with the sea urchin histone mRNA and Prof. Martin Billeter for providing me with the rabbit globin mRNA as RNA markers.