Distribution of H3-dimetacrine in rat cerebral cortex by electron microscopic autoradiography

Summary The cellular distribution of H³-dimetacrine in rat cerebral cortex was studied by electron microscopic autoradiography. A considerable proportion of autoradiographic grains (40.6%) was located over the synaptic areas, while the other structures (i.e., dendrites, axons, glial and neuronal cells) contained less autoradiographic activity.Acknowledgments. The authors wish to thank Siegfried AG., Switzerland, for the generous supply of 3-bromo-dimetacrine. Dimetacrine was kindly donated by Nippon Chemiphar Co., Ltd., Tokyo, Japan.