Increased erythrocyte permeability to Li and Na in the spontaneously hypertensive rat |
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| Authors: | S M Friedman M Nakashima R A McIndoe C L Friedman |
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| Institution: | (1) Department of Anatomy, Faculty of Medicine, The University of British Columbia, V6T 1W5 Vancouver, B.C., Canada |
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| Abstract: | Summary Red blood cells incubated in a physiological medium in which Li replaces Na (LiPSS) gain Li in exchange for Na and K. The rate of Li uptake is modestly but significantly increased in the spontaneously hypertensie rat (SHR) at 37°C and at 22°C. The slow rate of Na gain and K loss during cooling at 2°C was about doubled in unmodified whole blood samples from the SHR.This work was carried out with the aid of a grant from the British Columbia Heart Foundation. |
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