64排螺旋CT灌注成像在脑梗死早期诊断中的临床应用

探讨64排螺旋CT脑灌注成像（CTPI）对脑梗死超早期诊断的临床价值。对32例超早期脑梗死患者，均于发病6h内行CT平扫、CTPI检查，分析平扫及灌注成像表现，测量缺血区的脑灌注参数值。结果为32例患者中8例头颅CT平扫发现早期梗死征象，所有患者CTPI均发现脑灌注异常。脑梗死中心区脑血流量、脑血容量与对侧差异有极显著性意义（P〈0．01）；半暗带区脑血流量、达峰时间与对侧差异有极显著性意义（P〈0．01），而脑血容量差异无显著性意义（P〉0．05）。CTPI能够在脑梗死发病的超早期发现病变，明确梗死灶存在及其范围、位置，预测半暗带区域，对脑梗死的早期诊断和治疗有重要价值，具有广泛临床应用前景。

The Clinic Values of Brain Perfusion Imaging Using 64-row Spiral CT for Earlier Diagnosing the Cerebral Infarction

To investigate the clinic values of brain for earlier diagnosing the cerebral infarction. There perfusion imaging using 64-row spiral CT （CTPI） are 32 patients of cerebral infarction within supraearly period ,they were examined by CT plain scan and CTPI within 6 hours after onset, the image manifestation and the parameter value of cerebral perfusion in ischemic region were analyzed and evaluated. Only 8 cases showing positive manifestations with CT plain scan, all the 32 patients have brain perfusion abnormality in CTPI. The cerebral blood flow and blood volume in the core area of cerebral infarction are significant different from that of the opposite side （ P 〈 0.01 ）. In the semi dark band zone, the cerebral blood flow and the time to reach the peak also are significant from that of the opposite side （P 〈 0.01 ）, but the cerebral blood volume is not significant different from that of the opposite side （ P 〉 0.05 ）. CTPI is an effective method to easily find the early-stage cerebral infarction;it is very useful for early diagnosis and therapy, and may have a widespread perspective.