Histamine formation by ruminal fluid from cattle in vitro |
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| Authors: | A Wicki H J Schatzmann |
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| Institution: | (1) Veterinärpharmakologisches Institut der Universität Bern, Länggassstrasse 124, CH-3000 Bern, (Switzerland) |
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| Abstract: | Summary Net histamine formation in ruminal fluid is shown to be the result of histidine decarboxylation and histamine deamination. Addition of 4.7 mM histidine increased the rate of net histamine synthesis by a factor of 20 compared to normal. Histamine production sharply decreases at pH values below the physiological range. |
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