Effect of propranolol on various parameters of estrogen stimulation in the rat uterus

Summary Pretreatment with propranolol does not modify the estrogen-induced uterine eosinophilia, the water imbibition effect, nor the increase in uterine RNA and protein content. This confirms the independence of these parameters from the estrogen-induced early increase in uterine cAMP, since, when observed, the latter is suppressed by propranolol pretreatment.Acknowledgments. This work was supported by a contract of the Ministère de la Politique Scientifique, within the framework of the Association Euratom—University of Brussels—University of Pisa, and by grant 2015 from the Oficina Técnica de Desarrollo Científico y Creación Artística of the University of Chile.