基于相关维数的磁刺激穴位脑功能网络构建与分析

针灸经临床实践已证明其疗效,然而其作用机制仍不清楚,磁刺激穴位为研究针灸理论提供了一种新的方法.本研究采集安静状态和磁刺激内关穴(PC6)状态的脑电(EEG)信号,基于非线性动力学特征(相关维数)和互信息方法构建脑功能网络,基于复杂网络理论对所构建脑功能网络进行分析,对比分析了安静和磁刺激两种状态下的脑功能网络的拓扑性质.实验结果表明,基于磁刺激内关穴构建的脑功能网络与安静状态相比,其拓扑结构发生了改变,网络连接增强,信息传输效率提高,并且"小世界"属性增强.

Brain Functional Network Based on Correlation Dimension of EEG Under Magnetic Stimulation at Acupuncture Point

The therapeutic effectiveness of acupuncture has been proved by clinical practice. However, its effect mechanism is still unclear. Magnetic stimulation at acupuncture point provides a new way for studying the theory of acupuncture. In this study, a magnetic stimulation on Neiguan (PC6) acupoint was performed, and the corresponding EEG signals of quiescent and stimulated states were recorded. By using the feature of the non-linear dynamics (correlation dimension) and the mutual information method, brain functional networks were constructed and analyzed where the topology features of complex network were comparatively analyzed for the quiescent and stimulated states. The experimental results show that the topology of the network is changed and the connection of the network is enhanced. In additional, the efficiency of information transmission is also found improved and the "small-world" property tends to become stronger through stimulating PC6 acupoint.