| 着丝粒生物学 |
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| 引用本文： | 郭文久.着丝粒生物学[J].西华师范大学学报(哲学社会科学版),2008,29(1):4-9. |
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| 作者姓名： | 郭文久 |
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| 作者单位： | 安康学院化学与生命科学系,陕西安康725000 |
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| 基金项目： | 国家高新科技863项目(2001AA211171);安康学院高层次引进人才科研启动基金资助项目(2006) |
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| 摘 要： | 着丝粒的关键作用是保证细胞减数分裂和有丝分裂的顺利进行，保证生物的遗传．近年来随着对多个物种的着丝粒测序之后对着丝粒的功能提出了很多相互矛盾的假说．本文阐述了低等真核生物的着丝粒没有重复序列而高等真核生物的着丝粒具有大量的重复序列，并且简述了各物种着丝粒的组成和各类与组蛋白H3、核仁、着丝粒DNA序列及DNA的高级结构相关的着丝粒功能模型．
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| 关 键 词： | 着丝粒 重复序列 组蛋白 α-卫星DNA |
| 文章编号： | 1673-5072(2008)01-0004-06 |
| 修稿时间： | 2007年10月14 |
Centromere Biology |
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| GUO Wen-Jiu.Centromere Biology[J].Journal of China West Normal University:Natural Science Edition,2008,29(1):4-9. |
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| Authors: | GUO Wen-Jiu |
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| Institution: | GUO Wen-Jiu(Department of Chemistry , Life Science,Ankang University,Ankang,725000,China) |
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| Abstract: | The significant role of centromere is to perpetuate the process of mitosis and meiosis and maintain inheritance of organism.After centromeres in diverged species were sequenced in recent years,many competing models towards the explanation of centromere formation and function were raised.In this review,there is no repetitive sited in the region of functional centromere whereas there are a amount of repetitive sequences existed in that region.This review dictates the composition of centromeres in diverged org... |
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