| Synthesis of Novel Metal Ion Sensors Based on DNA-Metal Interactions |
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| 引用本文： | Akira Ono Shiqi Cao Hurnika Togashi Yoko Miyake. Synthesis of Novel Metal Ion Sensors Based on DNA-Metal Interactions[J]. 复旦学报(自然科学版), 2005, 44(5): 825-826 |
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| 作者姓名： | Akira Ono Shiqi Cao Hurnika Togashi Yoko Miyake |
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| 作者单位： | [1]Department of Applied Chemistry, Faculty of Engineering,-Kanagar.oa University, 3-27-1 Rokkakubashii,Kanagazoa-ku , Yokohama-shi , Kanagazoa-ken 221-8686,Japan [2]Department of Chemistry, Faculty of Science,Tokyo Metropolitan University, 1-1 Minami-ohsawa , Hachioji , Tokyo 192-0397,Japan |
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| 基金项目： | This work was supported in part by the grants-in-aids for Scientific Research (B)，The Mitsubishi Foundation，the National Project on Protein Structural and Functional Analyses，the Fund for Special Research Projects at Tokyo Metropolitan University |
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| 摘 要： | The interactions of metal ions with nucleic acids, nucleosides, and nucleo-bases have been extensively investigated .We have reported that thymine-thymine （T-T） and cytosine-cytosine （C-C） miss base pairs in DNA duplexes highly selectively capture Hgn ion and AgI ion, which result in formations of metal-mediated base pairs, T-Hg^Ⅱ -T and C-Ag^Ⅰ -C, in duplexes. The phenomenon is expected to be useful for a variety of studies such as synthesis of nano-wires containing metal ions, developing metal-ion sensing methods, etc. Here, we report novel oligodeoxyribonucleotide （ODN）-based sensors that detect Hgn ions and Ag^Ⅰ ions in aqueous solutions.
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| 关 键 词： | T-HgⅡ -T C-AgⅠ -C |
| 文章编号： | 0427-7104（2005）05-0825-02 |
| 收稿时间： | 2005-08-10 |
| 修稿时间： | 2005-08-10 |
Synthesis of Novel Metal Ion Sensors Based on DNA-Metal Interactions |
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| Akira Ono,Shiqi Cao,Humika Togashi,Yoko Miyake. Synthesis of Novel Metal Ion Sensors Based on DNA-Metal Interactions[J]. Journal of Fudan University(Natural Science), 2005, 44(5): 825-826 |
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| Authors: | Akira Ono Shiqi Cao Humika Togashi Yoko Miyake |
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| Abstract: | |
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| Keywords: | metal ion sensor DNA-metal interaction |
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