| 动物受精过程中卵子Ca2+释放机制 |
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| 引用本文： | 郑克刚,孟小倩,李云龙.动物受精过程中卵子Ca2+释放机制[J].山东师范大学学报(自然科学版),2006,21(3):120-122. |
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| 作者姓名： | 郑克刚 孟小倩 李云龙 |
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| 作者单位： | 山东师范大学生命科学学院动物抗性省重点实验室,250014,济南 |
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| 摘 要： | Ca^2＋是动物受精过程中卵内重要的第二信使，它对于皮质颗粒的排放、减数分裂的恢复、原核形成等过程具有重要的作用，受精过程中Ca^2＋的释放机制研究是当今受精生物学研究的热点之一，已有的研究结果表明动物卵子在受精过程中有三种Ca^2＋释放机制：由1，4，5，三磷酸肌醇引发内质网中储存的Ca^2＋释放、由环腺苷酸二核苷酸磷核糖引发与其相关联的钙库Ca^2＋释放和烟酸腺嘌呤二核苷酸磷酸引发的与其相关联的钙库Ca^2＋释放．
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| 关 键 词： | 受精 |
| 收稿时间： | 2005-12-18 |
| 修稿时间： | 2005-12-18 |
Ca2+ RELEASE MECHANISMS OF OOCYTE AT FERTILIZATION |
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| Zheng Kegang,Meng Xiaoqian,Li Yunlong.Ca2+ RELEASE MECHANISMS OF OOCYTE AT FERTILIZATION[J].Journal of Shandong Normal University(Natural Science),2006,21(3):120-122. |
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| Authors: | Zheng Kegang Meng Xiaoqian Li Yunlong |
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| Institution: | Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University,250014, Jinan, China |
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| Abstract: | Eggs from different animal species were studied to date elicit single or repetitive Ca~(2+) transients in(response) to fertilizing sperm.As an important second messenger,Ca~(2+) triggers a broad range of cellular reactions,(including) cortical granule release,completion of meiosis and pronuclear formation in oocyte.There are three mechanisms for Ca~(2+) release:inositol 1,4,5-trisphosphate pathway,cyclic ADP-ribose pathway and nicotinic acid adenine(dinucleotide) phosphate pathway. |
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| Keywords: | Ca2 IP3 cADPR NAADP |
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