| 国家自然科学基金重 |
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| 引用本文： | 点项目.国家自然科学基金重[J].贵州工业大学学报(自然科学版),2007(5). |
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| 作者姓名： | 点项目 |
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| 作者单位： | 40730424) |
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| 摘 要： | bution, surface morphology and surface charge of the paclitaxel-loaded nanoparticles were then investigated by laser light scattering, scanni
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| 关 键 词： | as used. The size and distri |
ng electron microscope and zeta pote |
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| ntial analyzer.ng electron microscope and zeta pote[J].Journal of Guizhou University of Technology(Natural Science Edition),2007(5). |
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| Authors: | ntial analyzer |
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| Abstract: | ile were measured by high-performance liquid chromatography (HPLC). Balloon injured rabbit carotid arteries were treated with single infusion of the paclitaxel-loaded NP suspension and observed for 28 days. The inhibitory effects of vascular smooth muscle cell migration and proliferation were evaluated as end-point. The NPs showed spherical shape with diameter ranging from 200 to 500 nm. The negatively charged PLGA NPs shifted to positive after the DMAB modification. The in vitro drug release |
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| Keywords: | profile showed a triphasic release pa |
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