| 嘧啶氧磷毒性和解毒试验研究 |
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| 引用本文： | 王茂风 杨泗溥. 嘧啶氧磷毒性和解毒试验研究[J]. 辽宁大学学报(自然科学版), 1998, 25(2): 147-150 |
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| 作者姓名： | 王茂风 杨泗溥 |
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| 作者单位： | 辽宁大学生物系，化工部农药安全评价监督检验中心 |
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| 摘 要： | 本文报道了嘧啶氧磷的急性经口，经皮毒性和解毒试验研究结果。嘧啶氧磷对小白鼠经口ＬＤ５０为８７ｍｇ／ｋｇ，大白鼠经口ＬＤ５０为１８３ｍｇ／ｋｇ，大白鼠经皮ＬＤ５０为１０６２ｍｇ／ｋｇ，氯磷定对嘧啶氧磷中毒有良好的解毒效果。
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| 关 键 词： | 嘧啶氧磷 解毒 毒性 有机磷杀虫剂 |
Studies on the Toxicity and Detoxication of N23 |
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| Wang Maofeng Biology Department,Liaoning University,Shenyang Yang Sipu Zhu Huixiang Supervision and Examination Center of Safty Evaluation of Pesticite,Ministry of Chemical Industry,Shenyang. Studies on the Toxicity and Detoxication of N23[J]. Journal of Liaoning University(Natural Sciences Edition), 1998, 25(2): 147-150 |
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| Authors: | Wang Maofeng Biology Department Liaoning University Shenyang Yang Sipu Zhu Huixiang Supervision Examination Center of Safty Evaluation of Pesticite Ministry of Chemical Industry Shenyang |
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| Affiliation: | Wang Maofeng Biology Department,Liaoning University,Shenyang 110036 Yang Sipu Zhu Huixiang Supervision and Examination Center of Safty Evaluation of Pesticite,Ministry of Chemical Industry,Shenyang110021 |
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| Abstract: | The toxicity and detoxication of N23, an organophosphorus insecticide, were studied in mice and rats. Oral LD 50 of the compound was 87 mg/kg to mice, 183mg/kg to rats. Its dermal LD 50 was 1062mg/kg to rats. The results of detoxication test shown that 2 pam chloride (2 pyridinealdoxime methochloride was efficacious antidote for mice treated by N23. |
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| Keywords: | N23 Detoxication 2-pam chloride. |
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