Bombesin promotes pancreatic growth in suckling rats |
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| Authors: | M Papp I Dobronyi G Varga C Scarpignato |
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| Institution: | (1) Institute of Experimental Medicine, Hungartan Academy of Sciences, Budapest, Hungary;(2) Laboratory of Clinical Pharmacology, Institute of Pharmacology, University of Parma, Parma, Italy |
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| Abstract: | Summary The pancreatic growth promoting effect of long term administration of bombesin was investigated in suckling rats. The authors showed that bombesin given in 10  g/kg b.wt doses s.c. every 8 h for 10 days from the day of parturition stimulated pancreatic growth: it increased pancreatic weight, protein and DNA content, trypsin and amylase activity and trypsin/DNA ratio. Conclusion: Bombesin is an effective stimulator of pancreatic growth in suckling rats. |
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| Keywords: | Bombesin pancreatic growth stimulation suckling rats |
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