| 纳米银—金复合颗粒对葡萄糖生物传感器响应灵敏度的增强效应 |
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| 引用本文： | 任湘菱 唐芳琼. 纳米银—金复合颗粒对葡萄糖生物传感器响应灵敏度的增强效应[J]. 科学技术与工程, 2002, 2(3): 15-16 |
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| 作者姓名： | 任湘菱 唐芳琼 |
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| 作者单位： | 中国科学院理化技术研究所,原中国科学院感光化学研究所部分,北京,100101 |
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| 基金项目： | 国家自然科学基金(69731010,69971023) |
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| 摘 要： | 以纳米银-金复合颗粒与聚乙烯醇缩丁醛(PVB)构成复合固酶膜基质,用溶胶-凝胶法固定葡萄糖氧化酶(GOD),组成葡萄糖生物传感器。实验表明,纳米颗粒可以使电极的响应电流从相应浓度的几十纳安增强到几千纳安。探讨了纳米颗粒效应在固定化酶中所起的作用,开辟了制备直接电子传递第三代生物传感器的新途径。
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| 关 键 词： | 憎水纳米银-金颗粒 固定化酶 葡萄糖氧化酶 生物传感器 |
| 修稿时间： | 2002-01-25 |
Enhancement of Glucose Biosensor Sensitivity by Addition of Ag-Au Nanoparticles |
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| REN Xiangling TANG Fangqiong. Enhancement of Glucose Biosensor Sensitivity by Addition of Ag-Au Nanoparticles[J]. Science Technology and Engineering, 2002, 2(3): 15-16 |
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| Authors: | REN Xiangling TANG Fangqiong |
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| Abstract: | Glucose biosensors have been formed with glucose oxidase(GOD)immobilized in composite immobilization membrane matrix,which is composed of Ag-Au nanoparticles and Polyvinyl butyral(PVB)by a sol-gel method.The experiments show that the current response is increased from tens of nanoamperometer(nA)to thousands of nanoamperometer to the same glucose concentration.The function of nanoparticles effect on immobilization enzyme is discussed. It can make a new method for preparation of the third generation biosensor of direct electron transfer. |
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| Keywords: | hydrophobic Ag-Au nanoparticles immobilization enzyme glucose oxidase biosensor |
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