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Three-dimensional structure of a complex of antibody with influenza virus neuraminidase |
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| Authors: | P M Colman W G Laver J N Varghese A T Baker P A Tulloch G M Air R G Webster |
| Abstract: | The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen-antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction therefore has some of the character of a handshake. |
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