2—芳氨基苄基（或甲基）环己酮肟的Beckmann重排反应

２－芳氨基苄基（或甲基）环己酮（１）与羟胺盐酸盐在过量氢氧化钠的乙醇和水溶液中回流，转变为２－芳氨基苄基（或甲基）环己酮肟（２），（２）可能为Ｅ或Ｚ构型，在多聚磷酸存在下，用甲苯为共溶剂，（２）能顺利进行Ｂｅｃｈｍａｎｎ重排反应，得到４个２－芳氨基苄基－５－己内酰胺和３个２－芳氨基甲基－５－己内酰胺（３），均为未见文献报导的新化合物。用元素分析，ＭＳ，ＩＲ，＾１ＨＮＭＲ，＾１３ＣＮＭＲ分析确定了它

THE BECKMANN REARRANGEMENT OF 2-ARYLAMINO-BENZYL(OR METHYL CYCLOHEXANONEOXIME

2-arylaminobenzyl(or methyl)-cyclohexanone (1) is prepared diedy by Mannich reaction. (1) can be converted to 2-arylarninobenzy 1 (or methyl) cyclohexanoneoxime (2) by refluxing with hydroxylamine hydrochloride and exass sodium hydroxide in ethanol-H2O solution. When (2) are treated with PPA and using toluene as cosolvent, they rearmnge to four new 2-aryaminobenzylmethyl-5-caprolactam and three new 2-arylandnornethyl-5-capro- lactam (3). The structure of (3) is dedued by elemental analysis, MS, IR, 1HNMR and 13CNMR. The structure of (3) confirms that (2) is Z configuration.