Electrically-induced mechanical activity of the isolated guinea-pig sciatic nerve. Influences of calcium and anoxia |
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| Authors: | Maria C da Silva M F Gimeno A L Gimeno |
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| Institution: | (1) Centro de Estudios Farmacológicos y de Principios Naturales, Obligado 2490, 1428 Buenos Aires, (Argentina);(2) Present address: Consejo Nacional de Investigaciones Cientificas y Técnicas de la República Argentina, República Argentina;(3) Conselho Nacional de Pesquisas do Brasil, Brasil;(4) Maternidade Climerio de Oliveira, Universidade Federal da Bahia, San Salvador, Bahia, Brasil;(5) Present address: the Consejo Nacional de Investigaciones Cientificas y Técnicas de la República Argentina (C.O.N.I.C.E.T.), Argentina |
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| Abstract: | Summary The electrically induced motility of isolated segments of guinea-pig sciatic nerves is reported. This motility was characterized by waves of tensional variations. The removal of Ca2+ from the suspending solution, the addition of EDTA as well as anoxia, resulted in a decrement of tension accompanied by a prolongued duration of the cycles of mechanical activity.This work was supported by grant 6638, from the Consejo Nacional de Investigaciones Cientificas y Técnicas de la República Argentina (C.O.N.I.C.E.T.). |
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