Effect of niacin/nicotinamide deficiency on the diabetogenic effect of streptozotocin |
| |
| Authors: | J R Wright J Mendola P E Lacy |
| |
| Institution: | Department of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110. |
| |
| Abstract: | Weanling CD-1 mice were fed either a control diet or a diet deficient in niacin/nicotinamide for one month and then injected i.v. with 60, 80, 100, 120, 140, or 160 mg/kg streptozotocin. Mice on the deficient diet developed a higher incidence of diabetes and more severe hyperglycemia than those on the control diet. |
| |
| Keywords: | |
|
|
