| 复方丹皮酚纳米乳中丹皮酚和灵芝多糖的含量测定 |
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| 引用本文： | 苏酩,袁敏,孙晓彤,隋在云. 复方丹皮酚纳米乳中丹皮酚和灵芝多糖的含量测定[J]. 山东科学, 2020, 33(6): 27-33. DOI: 10.3976/j.issn.1002-4026.2020.06.005 |
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| 作者姓名： | 苏酩 袁敏 孙晓彤 隋在云 |
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| 作者单位： | 山东省中医药研究院,山东 济南250014;潍坊弘景中医药学校,山东 潍坊261057 |
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| 基金项目： | 山东省重点研发项目（2015GSF119030,2018GSF119001,2018GSF119023） |
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| 摘 要： | 建立了复方丹皮酚纳米乳中丹皮酚和灵芝多糖的含量测定方法,丹皮酚测定选用HPLC法,灵芝多糖的测定采用蒽酮硫酸比色法。结果3批乳剂中丹皮酚、灵芝多糖的平均含量分别为7.612和6.127 mg/mL,平均包封率为97.99%,含量稳定均一,包封率高。该方法简便、准确可靠、重复性好,可作为复方丹皮酚纳米乳中丹皮酚和灵芝多糖的含量测定方法。
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| 关 键 词： | 复方丹皮酚纳米乳 丹皮酚 灵芝多糖 包封率 |
| 收稿时间： | 2020-03-23 |
Determination of paeonol and ganoderan content in Compound Paeonol Nanoemulsion |
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| SU Ming,YUAN Min,SUN Xiao-tong,SUI Zai-yun. Determination of paeonol and ganoderan content in Compound Paeonol Nanoemulsion[J]. Shandong Science, 2020, 33(6): 27-33. DOI: 10.3976/j.issn.1002-4026.2020.06.005 |
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| Authors: | SU Ming YUAN Min SUN Xiao-tong SUI Zai-yun |
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| Abstract: | Establish a method to determine the content ofpaeonol and ganoderan in Compound Paeonol Nanoemulsion. The paeonol content wasdetermined using HPLC. Determination of ganoderan was performed using theanthrone-sulfuric acid colorimetric method. The average contents of paeonol andganoderan in the three nanoemulsions were 7.612 and 6.127 mg/mL, respectively.The average encapsulation efficiency was 97.99%. The contents were stable anduniform, and the encapsulation efficiency was high. This method is simple,reproducible, accurate, and reliable. It can be used to determine paeonol andganoderan content in Compound Paeonol Nanoemulsion. |
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| Keywords: | Compound Paeonol Nanoemulsion paeonol ganoderan encapsulation efficiency |
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