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Trace metal requirements in total parenteral nutrition: A theoretical approach by mathematical modeling
Authors:G. Berthon  P. M. May  C. Matuchansky
Affiliation:(1) Laboratoire de Chimie I, Electrochimie et Interactions, Université de Poitiers, F-86022 Poitiers, (France);(2) Department of Chemistry, University of Wales, Institute of Science and Technology, CF1 3NU Cardiff, Wales;(3) Unité de Nutrition Entérale et Parentérale du Service de Gastroentérologie, CHU, Milétrie, F-86021 Poitiers, (France)
Abstract:Summary A new computer-based approach has been developed to assess the optimal doses of essential trace metal ions which should be included in nutritive mixtures, used in human total parenteral nutrition, to compensate for the ligand-induced losses of these metal ions. An example of application is given for zinc, copper and manganese.
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