Development of antral gastrin-like immunoreactivity and pituitary CCK8/gastrin-like immunoreactivity in rats |
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Authors: | H Okahata Y Nishi K Muraki K Sumii K Tanaka Y Miyachi T Usui |
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Institution: | (1) Department of Pediatrics and First Department of Internal Medicine, Hiroshima University School of Medicine, 734 Hiroshima, (Japan);(2) Department of Internal Medicine, Shizuoka General Hospital, 420 Shizuoka, (Japan) |
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Abstract: | Summary Gel filtration of antral extract of adult rats revealed gastrin-17 and gastrin-34. Gel filtration of anterior pituitary extract showed CCK8 and gastrin-17, whereas posterior pituitary extract showed only a CCK8. Antral gastrin-like immunoreactivity (G-LI) increased after milk feeding and especially after weaning was started. Changes in diet may exert a profound influence on the ontogenic development of antral G-LI, but not pituitary CCK8/G-LI. |
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Keywords: | Gastrin-like immunoreactivity CCK8/gastrin-like immunoreactivity antrum pituitary rat |
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