| 多功能磁性纳米药物载体的制备及表征 |
| |
| 引用本文： | 尚 乐,周庆翰. 多功能磁性纳米药物载体的制备及表征[J]. 西南民族大学学报(自然科学版), 2016, 42(5): 531-537 |
| |
| 作者姓名： | 尚 乐 周庆翰 |
| |
| 作者单位： | 西南民族大学化学与环境保护工程学院,西南民族大学化学与环境保护工程学院 |
| |
| 基金项目： | 自然科学基金青年项目（21404086） |
| |
| 摘 要： | 以AIBN为引发剂,以N,N'-双(丙烯酰)胱胺(BACy)为交联剂,与多巴胺丙烯酰胺(DMA)和聚乙二醇单甲醚甲基丙烯酸酯(PEGMA)发生共聚,同时加入Fe_3O_4磁性纳米粒子,制备得到纳米胶束.通过核磁(~1H-NMR),红外(FTIR),动态光散射(DLS)和透射电镜(TEM)等一系列手段对聚合物胶束的结构和形貌进行了表征,初步证明了制备的胶束具有还原响应性和良好的稳定性.
|
| 关 键 词： | 磁性纳米粒子 BACy 胶束 |
| 收稿时间： | 2016-06-06 |
| 修稿时间： | 2016-08-31 |
Synthesis and characterization of multifunctional magnetic nano drug carrier |
| |
| shangle and zhouqinghan. Synthesis and characterization of multifunctional magnetic nano drug carrier[J]. Journal of Southwest Minzu University (Natural Science Edition), 2016, 42(5): 531-537 |
| |
| Authors: | shangle and zhouqinghan |
| |
| Affiliation: | College of Chemistry&Environment Protection Engineering,Southwest University for Nationalities,College of Chemistry&Environment Protection Engineering,Southwest University for Nationalities |
| |
| Abstract: | A novel disulfide bonded cross-linked copolymer was synthesized using AIBN as initiator, N,N-bis(acryloyl) cystamine(BACy) as crosslinker,and the monomers also contain dopamine methacrylamide(DMA), polyethylene glycol ether methacrylate (PEGMA) and Fe3O4 magnetic nanoparticles, 1H-NMR,FTIR, DLS and TEM were utilized to investigate the chemical structure and micelle morphology.The results indicated that the micelles were stable and degraded in reducing agent. |
| |
| Keywords: | magnetic nanoparticles BACy micelle |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《西南民族大学学报(自然科学版)》浏览原始摘要信息 |
|
点击此处可从《西南民族大学学报(自然科学版)》下载免费的PDF全文 |
|
