首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Are stretch-sensitive channels in molluscan cells and elsewhere physiological mechanotransducers?
Authors:C E Morris
Institution:(1) Neurosciences, Loeb Institute, Ottawa Civic Hospital, 1053 Carling Ave, K1Y 4E9 Ottawa, Ontario, Canada
Abstract:Single-channel recordings of dozens of cell types, including invertebrate (molluscan) and vertebrate heart cells, reveal stretch-sensitive ion channels. The physiological roles of these channels are undoubtedly diverse but it is usually assumed that the roles they play are related to the channels' mechanosensitive gating. Whether this assumption is valid remains to be seen. Attempts to connect the single-channel observations with the mechanical aspects of physiological or developmental processes are discussed. In the case of molluscan cells, recent work suggests that their stretch channels have physiological functions unrelated to mechanosensitive gating.
Keywords:Stretch  mechanosensitive  ion channel  physiological role
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号