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染色体臂间倒位的遗传效应分析
引用本文:张爱萍,张学红,柳立军,王瑞艳,刘琨.染色体臂间倒位的遗传效应分析[J].甘肃科学学报,2009,21(3):105-107.
作者姓名:张爱萍  张学红  柳立军  王瑞艳  刘琨
作者单位:兰州大学,第一医院生殖中心,甘肃,兰州,730000
摘    要:对3516例就诊者进行外周血淋巴细胞染色体培养、收获、G显带(必要时C显带)后核型分析.结果检出染色体臂间倒位核型38例,异常检出率为1.08%.3、6、11号染色体各1例,Y染色体2例,9号染色体臂间倒位33例,遗传效应分析证明染色体臂间倒位与不孕不育、不良孕产史有关。

关 键 词:染色体异常  臂间倒位  遗传效应

Genetic Effect of Pericentric Inversion of Chromosome
ZHANG Ai-ping,ZHANG Xue-hong,LIU Li-jun,WANG Rui-yan,Liu Kun.Genetic Effect of Pericentric Inversion of Chromosome[J].Journal of Gansu Sciences,2009,21(3):105-107.
Authors:ZHANG Ai-ping  ZHANG Xue-hong  LIU Li-jun  WANG Rui-yan  Liu Kun
Institution:ZHANG Ai-ping,ZHANG Xue-hong,LIU Li-jun,WANG Rui-yan,Liu Kun(The Assisted Reproductive Center,The First Hospital of LanzhouUniversity,Lanzhou 730000,China)
Abstract:Our objective was to investigate the genetic effect of pericentric inversion of chromosome.The peripheral blood lymphocytic culture and harvest were performed in 3516 patients according to standard methods.Karyotype was analyzed after G or C band displaying.Results showed that among 3516 cases,38(1.08%) cases were found having pericentric inversion of chromosome,including 1 case of inv(3),1 case of inv(6),1 case of inv(11),2 cases of inv(Y) and 33 cases of inv(9).It was concluded that pericentric inversion ...
Keywords:chromosomal abnormity  pericentric inversion  genetic effect  
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