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At least two toxins are involved inEscherichia coli mastitis
Authors:B E Brooker  A J Frost  A W Hill
Institution:(1) National Institute for Research in Dairying, Shinfield, Reading, Berkshire, England;(2) Institute for Research in Animal Diseases, Compton, Newbury, Berkshire, England;(3) Present address: Department of Veterinary Pathology and Public Health, University of Queensland, Brisbane, Australia
Abstract:Summary Culture filtrate ofEscherichia coli produces changes in the bovine udder identical to those seen in experimental infections with the same organism.E. coli endotoxin produces an acute inflammatory response but none of the cell damage induced by culture filtrate. It appears therefore that at least 2 toxins are involved in the disease.Acknowledgments. We are grateful to Mrs K. Wells, Miss H. Meads and Miss A. Ashford for technical assistance.
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