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Immunogenetics
Authors:K. Bender
Affiliation:(1) Institut für Humangenetik and Anthropologie der Universität Freiburg i.Br., Albertstrasse 11, D-7800 Freiburg, (Federal Republic of Germany)
Abstract:Summary The 1985 Catalog of Mapped Genes (Human Gene Mapping 8; 33) has been used to pick out the known, immunologically important genes; these are then discussed in the following order: 1. genes controlling organs, tissues and cells of the immune apparatus, 2. genes determining lsquoselfrsquo structures, 3. genes determining the structures of immunological specificity, 4. genes determining substances with immunoregulatory and effector properties. The symbols for the genes and the biological functions of their products are explained. The genetics of the ABO blood groups, of the HLA-system and of antibody formation are given in rather more detail.
Keywords:Genes with immunological function  human gene map  ABO  HLA  immunoglobulins  immunoglobulin supergene family  interleukin  interferon  complement
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