Guanylate cyclase stimulation by nitro-compounds is dependent on free Ca2+1 |
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| Authors: | G Steurer W Schütz |
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| Institution: | (1) Department of Pharmacology, University of Vienna, Währinger Strasse 13a, A-1090 Vienna, (Austria) |
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| Abstract: | Summary The stimulatory effect of nitro-compounds on arterial and hepatic guanylate cyclase became significantly depressed at 0.2  M and higher concentration of free Ca2+. The basal enzyme activity proved to be Ca2+-independent.This study was supported by the Anton Dreher-Foundation for Medical Research. |
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| Keywords: | Pig carotid artery artery pig carotid guanylate cyclase nitro-compounds Ca2+ free |
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