MARS治疗重型肝炎疗效及影响因素分析

目的：分析MARs（分子吸附再循环系统）治疗重型肝炎的疗效及影响因素。方法：在综合治疗的基础上对123例重型肝炎患者进行MARS治疗，分析其疗效及重型肝炎的临床分型、分期、患者年龄、治疗次数对疗效的影响。结果：MARS治疗重型肝炎123例，治愈或好转48例，治愈好转率39％。MARS对早、中、晚期重型肝炎的治愈好转率分别为80．8％、46．5％、13％，对急性、亚急性、慢性重型肝炎的治愈好转率分别为14．3％、55．6％、42．9％。MARS治疗重型肝炎疗效与治疗次数不呈正相关，与患者的年龄有关。结论：MARS是治疗重型肝炎的有效方法，其疗效与患者年龄、重型肝炎的临床分型及分期有关，与MARS治疗次数不呈正相关。

Effect of MARS on Severe Hepatitis and Its Related Factors

To analyze the treatment effects of the molecular adsorbem recycling system （MARS） for severe hepatitis and the related factors. Method 123 patients with severe hepatitis were subjected to MARS as well as basic treatments. The effects of MARS and the related factors, such as the clinical types and stages of severe hepatitis, age of patients, and treatment times were analyzed. Result 48 patients were cured or improved （39%）. The cure rates of early, mediate and advanced severe hepatitis were 80.8%, 46.5% and 13% respectively and of acute, sub acute and chronic severe hepatitis were 14.3%, 55.6% and 42.9% respectively. The treatment effects of MARS had no positive relationship with the treatment times, but had some relationship with age. Conclusion MARS is effective in treating severe hepatitis, which is related to the age of patients and the clinical type and stage of severe hepatitis but not to the treatment times.